Yes, it can.
Most wrinkles will hang out on their own, although you can iron leather if you use care. Set the iron on its rayon setting, and use heavy brown wrapping paper as a pressing cloth on top of the area you wish to iron. Wrinkles should come right out.
As always, when doing something at home, test your procedure out on a small, inconspicuous section of the garment to see if there will be any problems. Or bring it to Sarni Cleaners. We'll clean your leather garments for you.